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As discussed, the interplay between astrocytes and microglia via modulation of GSH activity implies that GSH is not only a cellular antioxidant, but an important mediator of cross-talk between resident CNS immune cells

They contribute to cardiovascular events via inhibiting endothelial NO production and promoting superoxide production

For instance, CD44v6 targeting peptides Hv6pep, developed with the inclusion of 3 amino acids necessary for v6 interaction with coreceptors, induced a significant tumor growth reduction upon xenograft injection

The extracts were centrifuged at 10,000 rpm for 10 min at 4 C, and the supernatant was collected and used immediately for the assay at a dilution of 1:10 in PBS/EDTA