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1 2 "Multiple Sclerosis: Hope Through Research | National Institute of Neurological Disorders and Stroke"

It is important to note that while glutathione supplements can support the immune system, they should not replace a healthy lifestyle and proper medical care

Tumor cells heavily rely on Gln to counteract oxidative stress, yet recent studies demonstrate that glutamine deprivation or treatment with the glutamine analog DON induces epigenetic remodeling via trimethylation of histone H3K4me3, selectively upregulating HMOX1 transcription while inhibiting the activity of system Xc- subunit SLC7A11 and GPX4, thereby promoting lipid peroxidation-derived ROS accumulation and ultimately triggering ferroptotic cell death [63]

Use of validated scales (e.g., MoCA, GDS, HADS) in routine care is recommended