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What is the significance of elevated MMA levels in B12 deficiency

7 In desalting, typically a mild reagent with a lower salt concentration is employed, like 25 mM NaCl, to prevent possible ionic interactions, though more volatile buffers, like 100 mM ammonium acetate or ammonium hydrogen carbonate, can be used if necessary

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In this case, as also stated by the authors, the supplementation could be efficacious only if it is going to be prophylactically used prior to an H5N1 influenza infection