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Role of Carotenoids in Autoimmune Diseases Autoimmune diseases (ADs) are complex, multifactorial disorders characterized by loss of immune self-tolerance, leading to immune attacks on host tissues and consequent organ damage [77]

These cells normally exist in a quiescent state but become activated following muscle injury or mechanical stimulation, proliferating and fusing with existing muscle fibers to support hypertrophy and repair

Attenuated lymphocyte activation leads to the development of immunotolerance in bovine fetuses persistently infected with bovine viral diarrhea virusdagger