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Nicotine from a smoked cigarette will reach the brain in as little as 7 seconds after inhalation. The addictive effect of nicotine is linked to its capacity to trigger the release of dopamine a chemical in the brain that is associated with feelings of pleasure

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Of these fifty-two million, four out of five have tried to quit smoking and have faileda high failure rate, perhaps, but at least the present rate of attempts at self-reform is greater than it was when the Surgeon Generals report was issued

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