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Model establishment followed the reported protocol ( 2.3 Open field test (OFT) The OFT was conducted to assess anxiety-like behavior, exploratory activity, and locomotor function in mice

doi: 10.1002/adhm.202403933 171 HeQYangJPanZZhangGChenBLiSet al

An ideal future study would employ a biomarker-stratified, randomized, triple-blind, placebo-controlled trial to evaluate the comparative efficacy and mechanistic specificity of Rhodiola rosea , Ginkgo biloba , and Withania somnifera as adjuncts to first-line SSRI therapy in patients with major depressive disorder