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Current studies explore ultra-high dose B12 injections for neurodegenerative diseases and autism spectrum disorder

The enzymes COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin G2 (PGG2), the first step of the synthesis prostaglandins and thromboxanes that are involved in rapid physiological responses

ROC analysis yielded AUC values of 0.74 for patients versus controls and 0.62 for carriers versus controls (Supplemental Information, Table S4)

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