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Effects of parenteral glutamine supplementation on modulating the immune response in rats undergoing a total gastrectomy

Our earlier studies have shown that treatment of HT22 cells with glutamate activates PDI-mediated NOS dimerization, which is followed by accumulation of cellular NO and ROS, and ultimately, oxidative cell death [8]

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For example, while compound screening based on the Chemical Entities of Biological Interest (ChEBI) database identified targets like TREM1 and MAPK1, incomplete data made it harder to validate the results (Mallick et al., 2017