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The yakuchinones inhibited the iNOS and COX-2 expression as well as TNF- mRNA expression in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate (TPA)

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J Inherited Metab Dis 20 : 270285

Future research requiring direct comparison should consider designing studies that include: The primary distinction between Pinealon and traditional nootropics lies in their fundamental mechanisms of action, as summarized in the table below