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Vuilleumier S

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For example, page four of the patient brochure includes a presentation regarding the administration of Alymsys by intravenous infusion, but fails to disclose any material information that bevacizumab products, including Alymsys, can cause infusion-related reactions (IRR), including hypertension, hypertensive crises associated with neurologic signs and symptoms, wheezing, oxygen desaturation, Grade 3 hypersensitivity, chest pain, headaches, rigors, and diaphoresis. In addition, the limitations of use are not presented until page four, separate from the information on metastatic colorectal cancer

Compare that to the well-documented withdrawal syndromes associated with benzodiazepines and the rebound insomnia that follows discontinuation of most pharmaceutical sleep aids