glutathione increases in cancer cells Involvement of peroxidases the occurrence and development of breast cancers | Journal of Translational Medicine Glutathione metabolism in cancer progression

In June 2018, CBD was approved by the Food and Drug Administration (FDA), with the trade name of Epidiolex, as an anti-epileptic drug for patients (2 years of age and older) with Dravet or Lennox-Gastaut syndromes

For JAMs, they are a group of proteins belonging to the immunoglobulin superfamily

Additionally, while preclinical studies provide valuable insights, the translation of these findings to clinical practice remains challenging due to differences in experimental models, human disease complexity, and pro- and anti-inflammatory properties of 12/15-LOX

Enrichment analysis was performed using the GSEA software version 4.3.3 (Broad Institute) [33, 34], using gene sets from the Molecular Signatures Database (MSigDB), including the Hallmark, Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology Biological Process (GOBP) collections, and the cultured human stem cell classification Mueller Plurinet [35,36,37,38]