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In addition, berberine decreases obesity- and diabetes-related inflammation (167)

In vitro , in comparison with control, healthy animals, the assessment of splenic cells (day 21) demonstrated that the 6-methylprednisolone animals had declined reactivity to nitrogen, while the addition of BPC 157 (1 g/g cream) returned cell reactivity to normal values (Mikus et al., 2001

doi: 10.1017/S175173111700235X

As of that readout, overall survival showed a positive trend in favor of the Rybrevant combo, though this result did not reach statistical significance