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Sci Transl Med (2020) 12(540):eaay0605

Injections, however, are administered subcutaneously, often in the abdomen, allowing the peptide to circulate more directly through the body

That modification makes them highly toxic to liver cells

People with the following should discuss risks carefully with a medical professional: Liver disease Kidney disease Pernicious anemia Known allergies to any ingredient in the formulation Pregnancy or breastfeeding (safety not well-studied avoid unless prescribed) Because ingredients differ between providers, always verify the formulation and follow prescribed dosing to minimize risk