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Can nicotine help you lose weight? Nebraska Medicine Omaha, NE How Long Can Nicotine Stay in Your System? Effects of Cigarette Smoking on Metabolism and Effectiveness of Systemic Therapy for Lung Cancer Journal of Thoracic Oncology Smoking cigarettes affects many aspects of your body, including your physical endurance. If you smoke, you get less oxygen in your heart, lungs and muscles. This reduces your physical fitness level.
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