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c , d , Tumor growth curves ( c ) and tumor weights ( d ) in Rag1 / mice bearing non-adipose or WAT-enriched tumor models receiving adoptive transfer of activated CD8 + T cells from OT-1 mice on day 7 post-implantation (n = 6 mice per group)

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Since the FDA approved the first tyrosine kinase inhibitor (TKI), imatinib, in 2001, numerous small molecule targeted drugs have been introduced into clinical oncology [40]

EMBO Rep 17(1):2736 Tang B, Zhu J, Li J, Fan K, Gao Y, Cheng S, Kong C, Zheng L, Wu F, Weng Q, Lu C, Ji J (2020) The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma