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Furthermore, the mutations of either PINK1 or Parkin have been mentioned to be involved in early-onset familial PD [108]

E.RatnikovaI

MTHFR (Methylenetetrahydrofolate Reductase) is an enzyme that plays a key role in the process known as methylation

Estrogen peaks at proestrus before ovulation in females, followed by increased progesterone post-ovulation, suggesting varying effects on the circadian clock across reproductive cycle stages 75,76