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cerevisiae strain for glutathione overproduction To identify a GRAS yeast strain capable of high glutathione production, 30 wild-type yeast strains were batch-cultured in 100 mL flasks

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and ** P = 0.0054 and *** P = 0.0007 for non-supplemented and supplemented conditions for b

The cereblon-based PROTAC 121 , targeting sirtuins (Sirt) histone deacetylases, was shown to selectively degrade and inhibit target activity (IC 50 value of 0.25 M), thereby inducing downstream -tubulin hyperacetylation