MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95%

[O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

324 SMILES CC(C)(C)OC(=O)N1CCN(CCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name: 5-TAMRA-PEG3-azide Synonyms: 5-Carboxytetramethylrhodamine-PEG3-Azide CAS Number: 1228100-59-1 Molecular Formula: C33H38N6O7 Molecular Weight: 630

SiR-Azide is a far-red fluorescent probe containg azide moiety for click chemustry apploications

MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,