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164 LeeJ

10.1186/s12905-026-04323-3 11 FalkJ

Then, we assessed whether Smo mediates the role of Hh in regulating apoptosis

Ferroptosis is a form of iron-regulated cell death, which is distinguished from other traditional cell death programs by its morphological (shrunken mitochondria with increased membrane density), biochemical (accumulation of free iron and toxic lipid peroxidation, depletion of intracellular antioxidants), and genetic (involvement of many specific genes) features [19]