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Description

Avoid during pregnancy due to potential effects on fetal development

Sequence analysis Protein sequence alignments were calculated in Jalview 2.8.2 86 using Clustal W 87

However, Maiorino and co-workers recently redefined the catalytic motif of GPx1 as tetrad by establishing through mutagenesis study in Drosophila model that asparagine (Asn or N) residue was also essential for the catalytic activity of GPx1 [13]