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Instead, an iterative process of overlaying core genes should be used to achieve sufficient confidence in identifying molecularly and spatially segregated stable astrocyte subclasses (using five or more genes can provide near-absolute confidence in regions where a high-fidelity reference is available

Figure 2b, c illustrates the top ten driver genes showing upregulation and top ten suppressor genes showing downregulation in HMC, both selected based on the smallest p-values

Considering that the majority of our LC and R participants had a mild acute infection, confounding health conditions were not common ( Supplementary Table 1 )

B., Peixoto, T., Santos, R