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Since NRF2 activation induces the antioxidant and detoxifying response to restore redox homeostasis state, in recent years there has been a growing interest in identifying and evaluating new compounds capable of targeting the KEAP1-NRF2 system, to induce cytoprotective response against OS

( C ) The GMSG-enriched tumor-infiltrating CD8 + T cell cluster was found only in ICB_PR renal carcinoma patients (SCP1288

However, we cannot exclude the possibility of effects on other pain-related regions