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By inhibiting ECM1 and activating the GM-CSF/STAT5/Arg1 pathway to promote the differentiation of alternative macrophage M2, Shionone effectively diminishes the inflammatory response, thereby facilitating tissue repair and mitigating AKI

The precursor protein TG does not have iodine, and it is produced and packed in the rough endoplasmic reticulum and the Golgi apparatus, respectively, and then stored in the lumen of follicles via exocytosis

Polymer carriers (such as PLGA, chitosan) can precisely release drugs through stimulus responsive design (pH/temperature sensitivity) and can enhance tumor enrichment through surface targeting molecules (such as hyaluronic acid) (Danhier et al., 2012

The two cysteines can form a disulfide bond