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Notwithstanding this difference, the overall finding of lower GPx activity at 3 weeks of age might imply an over compensation by the elevated CAT activity causing a decrease in the substrate and therefore in GPx activity and its subsequent mRNA expression and perhaps also the higher TAS and unaltered levels of MDA between 2 and 12 weeks

The individual PEM threshold may reflect a variable reactivity of the neuroglial cells involved, i.e., their degree of priming and pre-existing impairment of their key physiological functions