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doi: 10.1016/j.marpolbul.2015.05.004 22 JinY.XiaJ.PanZ.YangJ.WangW.FuZ

10.1007/s00018-016-2314-y 141 MerkleF

This finding reveals the complex interplay between copper and immune responses, providing potential therapeutic targets for future PD treatment strategies, particularly in copper homeostasis regulation and immune response control (182)

These antioxidant enzymes represent the first line of defense and not only transform two main ROS: O 2 into H 2 O 2 and consequently H 2 O 2 to H 2 O, but also prevent the formation of damaging OH via the catalytic decomposition of H 2 O 2 (the Fenton reaction)