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The liver, which is the main organ for drug metabolism, is at a particular risk of adverse effects with respect to herbal and nutraceutical agents subject to extensive hepatic biotransformation or induction/inhibition of cytochrome P450 (CYP) enzymes (212)

What began as a wound-healing observation has since evolved into one of the most studied tripeptides in dermatological research, with documented effects on collagen synthesis, matrix metalloproteinase regulation, and oxidative stress modulation

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