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214 SchneiderR

Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

Common neurological manifestations include: Paraesthesia (pins and needles) in the hands and feet Numbness and altered sensation Difficulty with balance and coordination (ataxia) Memory problems and cognitive impairment Mood changes, including depression and irritability In severe cases, visual disturbances and confusion These neurological features arise from demyelination of peripheral nerves and the spinal cord, a condition known as subacute combined degeneration when it affects the posterior and lateral columns of the spinal cord

690,697 GPX4 is localized in the nucleus of oligodendrocytes, and liproxstatin-1 can restore the expression of GSH and GPX4 and inhibit mitochondrial lipid peroxidation, thus reducing the ferroptosis of oligodendrocytes, which is also a way to improve SCI