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A possible explanation for this apparent contradiction is that Cys63 is involved in a transient interaction with TRX prior to the formation of the final TRXTXNIP complex

Seedlings were cultured in 1/2 MS liquid medium containing 50 M oryzalin for 6 h or 50 M PAO for 1.5-h before being observed by confocal microscopy

Furthermore, high ROS levels trigger the apoptotic cascade by cleaving caspase 8 (CAS-8) and subsequently activating caspase 3 (CAS-3), which in turn degrades nucleic acids 40