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Transgenic strains were generated by injecting the DNA mixture into the gonads of young adult worms using the standard C

FIGURE 3 The first choline-TMA lyase inhibitor, DMB, was identified by Wang and colleagues, which is shown to non-lethally inhibit distinct microbial TMA lyases, and reduce TMAO levels in mice fed a high-choline or L-carnitine diet (Wang et al., 2015)