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The bloodstream carries Vitamin C supplements directly to your skin, which works alongside topical applications

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doi: 10.1073/pnas.1304790110 111 De VeirmanKMenuEMaesKDe BeuleNDe SmedtEMaesAet al

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It also reduced the release of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1, which were triggered by ethanol exposure, improved energy homeostasis in the ileum, and reversed the downregulation of mRNA and protein expression of key tight junction proteins in the ileum, specifically ZO-1, Claudin-1, and Occludin, thereby restoring their functional integrity

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