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Microglia and astrocytes fractal analysis was performed as described ( Supplementary Figure 2 ): colorized images ( Supplementary Figure 2a ) were transformed to 8-bit grayscale to best visualize all positive staining ( Supplementary Figure 2b )

In contrast, resistant WK ducks showed a significant increase in IgM (though lower than in susceptible WK ducks) alongside stable IgG and IgA ( p 0.05)

Alternatively, PZA can be initially oxidized to 5-hydroxy-pyrazinamide (5-OH-PZA) by XO, followed by amidase-mediated hydrolysis to 5-OH-PA

They can be loaded with chemotherapeutic agents, gene therapy vectors, or photothermal and photodynamic therapy (PDT) agents, effectively inducing tumor cell destruction