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If inflammatory reactions are a necessary prelude to FISS, then these rates suggest that 1 in 35 to 40 inflammatory reactions develop into FISS

Circulation 124:17651773 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M et al (2008) Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography

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These cells can be injected into the body either directly into a diseased and damaged area or introduced through an IV infusion directly into the bloodstream