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It is to be noted here that in case of pH 10.0, although the secondary and tertiary structure of hPrdx6 differs from that of the cytosolic conformer, it remained dimeric and functionally peroxidase active, thereby buttressing the importance of quaternary structure in determining the functional property of hPrdx6 enzyme

Additionally, Epitalon exhibits antioxidant activity by reducing lipid peroxidation and regulating reactive oxygen species (ROS)

there is no large human RCT for either

In some embodiments, the otic formulation or composition comprises about 0.03% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof