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We tested the binding of GATA-1 to the CGATA element using ChIP assays in wildtype and Tet2 knockout cells and as expected found reduced GATA-1 binding to the CGATA +33 kb site in the c-Kit promoter in knockout cells where methylation levels are higher (Fig

faecium between UK and Ireland, Denmark and Australia further highlighted the potential for clinically relevant clones to disseminate between hospitals [76, 90, 100]

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Quick Answer: Potentially yes they work through different pathways and may be complementary but this combination requires careful medical supervision and has not been studied in clinical trials