Dependent on the form of ADT used, build-up of steroid precursors occurs that are shunted to the synthesis of other steroids, such as progesterone (e.g., treatment with CYP17A1 inhibitor abiraterone), some of which can stimulate CaP progression via co-occurring accommodating changes in AR [35]
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these are regulated as foods under Food Standards Agency (FSA) rules rather than as medicines, and are therefore not subject to the same rigorous clinical evaluation as licensed medicinal products
Heterogeneity of diagnoses presenting as cyclic vomiting
