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Figure 1 2.1 Hormonal and endocrine dysregulation Estrogen dependency and progesterone resistance are central to the hormonal and endocrine dysregulation driving endometriosis-associated infertility, facilitating ectopic endometrial implantation through impaired apoptosis, heightened inflammation, and aberrant neuroangiogenesis ( de novo synthesis within ectopic lesions and enhanced estrogen receptor signaling

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Although we consider that this period could have been enough for the neurometabolic activity (occurring during the fMRI block) to return to baseline, there are no definitive parameters regarding the time that neurometabolites return to baseline levels after cognitive effort

doi: 10.1038/s41598-017-05051-3