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ADO levels in BM plasma samples from MM patients were compared with those from patients with precursor forms of monoclonal gammopathy of undetermined significance (MGUS) and smoldering MM (SMM)

Lipolysis Enhancement and Lipogenesis Inhibition In obese Zucker rats, daily oral administration of AOD9604 significantly increased lipolytic activity in adipose tissue compared to controls, establishing direct adipocyte-level lipolysis stimulation as a key mechanism of action in pre-clinical models

As a transmembrane glycoprotein with receptor-mediated adhesion function and ectoenzymatic activity, CD38 is ubiquitously expressed on MM cells, as well as some regulatory T cells (Tregs) and natural killer (NK) cells [5, 6]

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