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Mong J Agric Sci 13(2):124130 Eustquio AS et al (2005) Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters

The distal promoter region contains several CAAT boxes and TATA-like sequences, as well as binding sites for nuclear factor 1 (NF-1), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B), CCAAT/enhancer binding protein (C/EBP), the glucocorticoid receptor (GR), and activating protein 1 (AP-1) (101)

Although it demonstrated low predictive power, this model had the highest AUC among the previously reported models: MELD (0.522), MELD-Na (0.623), MELD 3.0 (0.543), CLIF-ACLF score (0.650), CLIF-C OFs (0.676), and CLIF-SOFA score (0.640)

In a STZ-induced DN rat model, BBR alleviated renal damage by reducing fasting blood glucose levels, kidney-to-body weight ratio, 24-h proteinuria, creatinine (Cr) and blood urea nitrogen (BUN) concentrations