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10.1067/mai.2003.17

Although the highest PUFA content is found in adipose tissue, PUFA in brain tissue accounts for 30%35% of the total fatty acid content, so the central nervous system is very vulnerable to lipid peroxidation (Peng et al., 2021)

Longitudinal variation of amino acid levels in human milk and their associations with infant gender

Regarding the modulation of the expression of MMPs, proteins that promote the remodeling of the extracellular matrix (ECM) [59] , melatonin achieves this repressive effect by inhibiting the p38 MAPK signaling pathway through PKA, exerting a negative effect on transcription by NF-kB, and even by docking directly at the MMP-9 activation site [28,62]