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Somatostatin interaction and GH pulse gating research Hypothalamic somatostatin tonically suppresses GH release and gates the timing of GH pulses through SSTR2/SSTR5 receptor signalling in somatotrophs

Methods 249 , 99105 (2015)

As will be further discussed in section Aging and age retaled diseases, IGF-I and GH levels also decrease with aging (somatopause)[169], reason why a potential strategy for reversing these senile changes in thymic vitality may involve administration of either GH or IGF-I, which have been examined for their potential to expand T-cell populations in animals[170]

To this end, we measured two stable post-translational modifications of protein tyrosine residues, 3-NT and 3-chlorotyrosine (3-CT)