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naturally small molecular reducing agents will never be as specific as the substrate-specific enzymes of the well-controlled antioxidant machinery of the cell, however with a finely tuned and designed thiolate basicity the redox potential and therefore the selectivity of the antioxidant thiol can be confined to a narrower range

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Studies examining the early treatment of AIH, the most active period of drug titration, are limited in part due to difficulties in reliably pinpointing the date of diagnosis in large electronic health records

This physiological mechanism, which is useful for the post-translational modification of multiple proteins and for the regulation of signal and metabolic pathways, can turn harmful in case of oxidative stress, with the above-mentioned mitochondrial damage