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A similar proportion of adults reported adverse events across all three groups in the study

Mean weight reductions were greater with all cagrilintide doses (roughly 6.0% to 10.8%) than with placebo (3.0%), and the top 4.5 mg dose modestly out-performed the active comparator, once-daily liraglutide 3.0 mg (10.8% vs 9.0%)

Semaglutide and tirzepatide also reduce liver fat, with tirzepatide generally showing greater reductions than semaglutide, but neither approaches the 80%+ reductions seen with retatrutide

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