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While the mitochondrial thiamine partners described above clearly make vitamin B1 extremely important for energy homeostasis, its role as a cofactor of cytosolic transketolase is also very interesting since this enzyme catalyzes the first and last step of the pentose phosphate pathway allowing, on the one hand, NADPH production which is required to cellular antioxidant defenses (as a cofactor of glutathione reductase in particular) (Figure 2), and on the other hand, ribose generation for nucleotide synthesis

If you prefer evening supplementation and experience no sleep disturbances, there is no medical reason to change your routine

Choline: Choline is an essential nutrient that supports liver health and fat metabolism

The brand we use is 5ml per 100lbs,which is the same lol