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In this fashion, we hope to provide data that will support our conclusion that the intestinal paracellular space is a major route of transport of water and small solutes such as ions and small soluble organic molecules between the lumen and submucosal space, and not a means by which large molecules, lipophilic substances, or macromolecular structures such as proteins, particulate matter, or intact bacteria are absorbed

References [1] Kraus, D., et al

Chronic ethanol exposure can lead to BBB disruption through the activation of microglia and the release of pro-inflammatory mediators