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Aguilar-Arnal, L

During this process, the nerve sends chemical signals and nutrients to the site of the injury

Anti-inflammatory microglia release factors that promote neuronal survival and tissue healing, effectively dampening the inflammatory response once the threat has been removed [144]

Additional tyrosinase inhibitors with clinical evidence on melasma and/or PIH include azelaic acid [25, 27, 67, 90], kojic acid [27, 66, 90], cysteamine [7, 91,92,93], and several actives from licorice extracts such as glabridin, liquiritin, and isoliquiritin [27, 94], as well as resveratrol and some of its derivatives [73, 95]