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Description

The hMPV F polypeptide or nucleic acid molecule of claim 8 or 9, wherein said prefusion F polypeptide comprises an amino acid substitution replacing the amino acid at position 160 with phenylalanine, tryptophan, tyrosine, valine, alanine, isoleucine or leucine

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40 In addition, human meningeal cells treated with a SMAD3 inhibitor were able to attenuate TGF 1-dependent MMP9 upregulation

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