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TP53 germline mutations Germline mutation of TP53 in the heterozygous LOF form usually presents with a rare autosomally dominant genetic disease with a significantly increased risk of cancer development known as Li-Fraumeni syndrome (LFS)

Therefore, the ability to clear the infection via SOD pathway appeared to be a distinct mannerism and is not dependent on macrophage activation and differentiation

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Volosin M et al (2006) Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins