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The combination could theoretically protect against the muscle wasting that sometimes accompanies aggressive caloric restriction

Pharmaceutics 15:452 Bojarska J, Mieczkowski A, Ziora ZM, Skwarczynski M, Toth I, Shalash AO, Parang K, El-Mowafi SA, Mohammed EH et al (2021) Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold