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Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial

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Structural determination and refinement Structural determination of reduced OsDHAR was performed by the molecular replacement method with the MOLREP program by using a homology model of OsDHAR generated by the SWISS-MODEL server 32 and the coordinates of human CLIC1 as the template structure 12