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In summary, direct or indirect regulation of mitophagy abnormality can alleviate the neurological damage caused by a extracellular amyloid plaque deposition, -synaptic nucleoprotein accumulation, dopaminergic neuron loss, neuroinflammation, and OS, and play an essential role in the physiopathological process of NDD

10.1016/j.stem.2014.09.017 70 GrimmigB.DalyL.HudsonC.NashK.BickfordP

Patel is a Midwest native

The introduction of chitosan into a biopolymeric scaffold (i.e., PLA/chitosan scaffolds) results in improved mechanical and biological functionality [54]